2-(Trifluoromethyl)benzoic acid → 2-(Methylthio)-6-(trifluoromethyl)benzoic acid

반응식

CO[C:3]1[CH:11]=[C:10]([C:12]([F:15])([F:14])[F:13])[CH:9]=[C:8]([S:16][CH3:17])[C:4]=1C(O)=O.FC(F)(F)C1C=CC=CC=1[C:22]([OH:24])=[O:23].CSSC>>[CH3:17][S:16][C:8]1[CH:4]=[CH:3][CH:11]=[C:10]([C:12]([F:13])([F:14])[F:15])[C:9]=1[C:22]([OH:24])=[O:23]

참가 물질

반응물 3

HCID 98992-(Trifluoromethyl)benzoic acid

HCID 12232Dimethyl Disulfide

HCID 591979212-Methoxy-6-methylsulfanyl-4-trifluoromethyl-benzoic acid

생성물 1

HCID 591979032-(Methylthio)-6-(trifluoromethyl)benzoic acid

실험 절차

The title compound, white solid, MS: m/e=235.0 [(M−H)−], was prepared in accordance with the general method of intermediate A from 2-(trifluoromethyl)benzoic acid and dimethyl disulfide.

출처 및 근거

ORD 기록: ord-10dc0602ae0f4508b605142c6366b15d
출처 데이터셋: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08080541B2

반응 노트

불러오는 중…