Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 2-iodo-4-(trifluoromethyl)benzoate → 2-Cyclobutyl-4-trifluoromethyl-benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 2-iodo-4-(trifluoromethyl)benzoate | HCID 59438424 | — |
| 반응물 | 2-Cyclopropyl-4-(trifluoromethyl)benzoic acid | HCID 59438485 | — |
| 반응물 | HCID 178419766 | HCID 178419766 | — |
| 생성물 | 2-Cyclobutyl-4-trifluoromethyl-benzoic acid | HCID 59438432 | — |
반응 단계
The title compound, white solid, MS: m/e=243.0 [(M−H)−], was prepared in accordance with the general method of intermediate K from 2-iodo-4-trifluoromethyl-benzoic acid methyl Ester and cyclobutylzincbromide followed by saponification with sodium hydroxide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08080541B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-459820a8946d40eab6c887b0d71dd365 |
| 출처 메모 | uspto-grants-2011_12 |