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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 659241생성일: 2026년 10월 25일

1,4-Dibromo-2-butanol → cis-N-[2-(3-Hydroxy-pyrrolidin-1-yl)-cyclohexyl]-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide

https://huagongshe.com/reaction/659241

반응식

참여 물질

역할이름HCID투입량
반응물1,4-Dibromo-2-butanolHCID 29570—
반응물cis-N-(2-Amino-cyclohexyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamideHCID 58062914—
생성물cis-N-[2-(3-Hydroxy-pyrrolidin-1-yl)-cyclohexyl]-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamideHCID 58062933—

반응 단계

The title compound, light yellow foam, MS: m/e=433.2 [(M+H)+], was prepared in accordance with the general method of example 10 from cis-N-(2-amino-cyclohexyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide (intermediate I) and 1,4-dibromo-2-butanol. The two diastereomers were not separated.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08080541B2
출처 데이터셋uspto-grants-2011_12
ORD IDord-33ccdd02a4614fbbacbe2ffa7cae0f59
출처 메모uspto-grants-2011_12