돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 659267생성일: 2026년 10월 26일

2,4-Bis(trifluoromethyl)benzamide → 2-Methoxy-6-methylsulfanyl-N-[(1RS,2SR)-2-(4-oxo-piperidin-1-yl)-cyclopentyl]-4-trifluoromethyl-benzamide

https://huagongshe.com/reaction/659267

반응식

참여 물질

역할이름HCID투입량
반응물2,4-Bis(trifluoromethyl)benzamideHCID 2736099—
반응물1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodideHCID 11097568—
반응물N-((1RS,2SR)-2-Amino-cyclopentyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamideHCID 66681196—
생성물2-Methoxy-6-methylsulfanyl-N-[(1RS,2SR)-2-(4-oxo-piperidin-1-yl)-cyclopentyl]-4-trifluoromethyl-benzamideHCID 66681255—

반응 단계

The title compound, yellow gum, MS: m/e=431.3 [(M+H)+], was prepared in accordance with the general method of intermediate J from N-((1RS,2SR)-2-amino-cyclopentyl)-2-methoxy-6-methylsulfanyl-4-trifluoromethyl-benzamide (intermediate O) and 1-ethyl-1-methyl-4-oxo-piperidinium iodide.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08080541B2
출처 데이터셋uspto-grants-2011_12
ORD IDord-8acf14e1272d42778769c8feec2f3a64
출처 메모uspto-grants-2011_12