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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 659547생성일: 2026년 10월 25일

1-((4-Methoxyphenyl)methyl)piperazine → (4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-[4-(4-methoxybenzyl)piperazin-1-yl]methanone

https://huagongshe.com/reaction/659547

반응식

참여 물질

역할이름HCID투입량
반응물1-((4-Methoxyphenyl)methyl)piperazineHCID 231905—
반응물4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acidHCID 46906718—
생성물(4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-[4-(4-methoxybenzyl)piperazin-1-yl]methanoneHCID 58327787—

반응 단계

4-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 1-(4-methoxybenzyl)piperazine as in General Procedure 10 to give the title compound. LCMS: m/z=636.02 (M+H+); retention time=0.61 minutes.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08080561B2
출처 데이터셋uspto-grants-2011_12
ORD IDord-3aaf04e7e4dd478b897c6e0eeccfde51
출처 메모uspto-grants-2011_12