Formic Acid → N-Pyridin-2-ylmethyl-formamide

HRID 66017노트

반응식

HRID 66017 반응식
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1.[CH:9](O)=[O:10]>>[CH:9]([NH:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1)=[O:10]

참가 물질

3

반응물 2

HCID 284Formic AcidHCID 195092-Pyridinemethanamine

생성물 1

HCID 12228441N-Pyridin-2-ylmethyl-formamide

실험 절차

A mixture of 32.4 g. of 2-aminomethylpyridine and 96 ml. of 97% formic acid is heated under reflux for 3.5 hrs. The resulting solution is subjected to vacuum distillation, the desired product being isolated as the fraction boiling at 120° C./0.03 mm, 37.3 g. The product which is isolated as a yellow oil crystallized to a solid having a melting point at about room temperature.

후처리

  1. additionA mixture of 32.4 g
  2. temperatureunder reflux for 3.5 hrs
  3. distillationThe resulting solution is subjected to vacuum distillation

출처 및 근거

ORD 기록
ord-4c9dfbe434ad493aa3a7209d2dc84df3
출처 데이터셋
uspto-grants-1978_12
특허 번호
US04129567

반응 노트

불러오는 중…