Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nitric Acid → 4-amino-3-nitrophenylPropanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nitric Acid | HCID 944 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | 4-Aminohydratropic acid | HCID 43026 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 4-amino-3-nitrophenylPropanoic acid | HCID 12226817 | — |
반응 단계
A solution of 2-(4-Aminophenyl)propanoic acid (8.45 g, 51.2 mmol) in AcOH (70 mL) was added HNO3 (60%, 5.66 g) at room temperature. The reaction mixture was refluxed for 4 hrs then cooled to room temperature. The mixture was poured into iced water (200 mL), and extracted with CH2Cl2. The organic layer was dried over MgSO4, filtered, and concentrated in vacuo.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08084484B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-19d595998b3a4f71862231140536bfd5 |
| 출처 메모 | uspto-grants-2011_12 |