Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(4-Nitrophenyl)propionic acid → 4-Aminohydratropic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(4-Nitrophenyl)propionic acid | HCID 89244 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4-Aminohydratropic acid | HCID 43026 | — |
반응 단계
To a stirred solution of 2-(4-nitrophenyl)propionic acid (2.05 g) in THF (20 mL) and EtOH (20 mL) was slowly added 10% Pd/C (0.21 g) at room temperature. After hydrogenated for 2 h with H2 balloon, the reaction mixture was filtered through celite pad and washed with EtOH. The filtrate was concentrated in vacuo to afford the product as pale brown solid. (1.75 g, quantitative)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08084484B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-ae78d0401a8b4ca7a923ce6f9ad8b273 |
| 출처 메모 | uspto-grants-2011_12 |