Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(4-Nitrophenyl)propionic acid → 4-Aminohydratropic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(4-Nitrophenyl)propionic acid | HCID 89244 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4-Aminohydratropic acid | HCID 43026 | — |
반응 단계
A mixture of 1 (6.7 g, 1 mmol) in THF (100 ml) and EtOH (100 ml) is slowly added 10% Pd/C (680 mg) at room temperature. The reaction mixture is hydrogenated for 24 h with H2 balloon at room temperature. The mixture is filtered through celite pad and washed with EtOH. The filtrate is concentrated in vacuo.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08084484B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-fdc8fedb933d421686298bc443ce1c81 |
| 출처 메모 | uspto-grants-2011_12 |