Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Azobisisobutyronitrile → Bromo-(2-iodophenyl)-acetic Acid Methyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Azobisisobutyronitrile | HCID 6547 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | Methyl 2-(2-iodophenyl)acetate | HCID 640185 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | Bromo-(2-iodophenyl)-acetic Acid Methyl Ester | HCID 86632576 | — |
반응 단계
A mixture of (2-iodophenyl)-acetic acid methyl ester (14.5 g, 52.5 mmol), NBS (18.7 g, 105 mmol) and AIBN (1.72 g, 10.5 mmol) in CCl4 (300 mL) is refluxed for 10 h. The mixture is cooled to RT and the precipitate filtered. The filtrate is evaporated to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08084448B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-db93df6fcc214a318294e7c39ea96e68 |
| 출처 메모 | uspto-grants-2011_12 |