Water → 2-Methylsulfanylbenzene-1,3-diol

HRID 660625노트

반응식

HRID 660625 반응식
C[O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9]C)[C:4]=1[S:11][CH3:12].B(Br)(Br)Br.O>C(Cl)Cl>[CH3:12][S:11][C:4]1[C:5]([OH:9])=[CH:6][CH:7]=[CH:8][C:3]=1[OH:2]

참가 물질

5

반응물 3

HCID 962WaterHCID 25134Boron tribromideHCID 6035511,3-Dimethoxy-2-(methylthio)benzene

생성물 1

HCID 688384622-Methylsulfanylbenzene-1,3-diol

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To a solution of 1,3-dimethoxy-2-methylsulfanylbenzene (2.8 g, 15 mmol) in methylene chloride (40 mL) is added BBr3 (30 mL, 30 mmol, 1M in methylene chloride) and the mixture is stirred at RT for 18 h. Water is added and the organic phase is washed with water and brine then is dried over sodium sulfate. The solvent is removed under reduced pressure to give the title compound as a pink solid.

후처리

  1. washthe organic phase is washed with water and brine
  2. dry with materialthen is dried over sodium sulfate
  3. customThe solvent is removed under reduced pressure

출처 및 근거

ORD 기록
ord-3ec0328fb0414ce58ff7ecdc49182672
출처 데이터셋
uspto-grants-2011_12
특허 번호
US08084448B2

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