1-Vinylcyclohexyl alcohol → 5-{2-Hydroxy-4-[2-(1-hydroxycyclohexyl)-ethyl]-phenyl}-1,1-dioxo-1,2,5-thiadiazolidin-3-one

HRID 660716

반응식

HRID 660716 반응식
C([O:8][C:9]1[CH:14]=[C:13](I)[CH:12]=[CH:11][C:10]=1[N:16]1[S:20](=[O:22])(=[O:21])[NH:19][C:18](=[O:23])[CH2:17]1)C1C=CC=CC=1.[CH:24]([C:26]1([OH:32])[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1)=[CH2:25]>>[OH:8][C:9]1[CH:14]=[C:13]([CH2:25][CH2:24][C:26]2([OH:32])[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]2)[CH:12]=[CH:11][C:10]=1[N:16]1[S:20](=[O:21])(=[O:22])[NH:19][C:18](=[O:23])[CH2:17]1

참가 물질

3

반응물 2

HCID 747411-Vinylcyclohexyl alcoholHCID 688386435-(2-Benzyloxy-4-iodophenyl)-1,1-dioxo-1,2,5-thiadiazolidin-3-one

생성물 1

HCID 577773135-{2-Hydroxy-4-[2-(1-hydroxycyclohexyl)-ethyl]-phenyl}-1,1-dioxo-1,2,5-thiadiazolidin-3-one

실험 절차

The title compound is prepared from 5-(2-benzyloxy-4-iodophenyl)-1,1-dioxo-1,2,5-thiadiazolidin-3-one and 1-vinyl-cyclohexanol analogous to Example 44: (M−1)−=353; HPLC retention time=1.35 min (method A).

출처 및 근거

ORD 기록
ord-b06c8c8ba55b4c9eb9a2f83fd37dce47
출처 데이터셋
uspto-grants-2011_12
특허 번호
US08084448B2

연결된 노트

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