참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Benzyl 2-(benzyloxy)-4-chlorobenzoate | HCID 66989997 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-(Benzyloxy)-4-chlorobenzoic acid | HCID 22452154 | — |
반응 단계
To a solution of 2-benzyloxy-4-chlorobenzoic acid benzyl ester in EtOH (500 mL) is added 1N NaOH (100 mL) and the mixture is stirred at 60° C. for 24 h. The mixture is allowed to cool to RT and is acidified with 1N HCl. The volume of the solution is reduced to 250 mL and the resulting precipitate is filtered, washed with water and dried to give the title compound as an off-white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08084448B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_12 |
|---|
| ORD ID | ord-838b99b9482146618fe143d268dbdd53 |
|---|
| 출처 메모 | uspto-grants-2011_12 |
|---|
