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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 661556생성일: 2026년 10월 27일

Tetramethylammonium fluoride → (R)-2-(3,4-dichloro-benzoyl)-4-hydroxy-2-propyl-pyrrolidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/661556

반응식

참여 물질

역할이름HCID투입량
반응물Tetramethylammonium fluorideHCID 67803—
반응물(R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-propyl-2-(3,4-dichloro-benzoyl)-pyrrolidine-1-carboxylic acid tert-butyl esterHCID 66687873—
생성물(R)-2-(3,4-dichloro-benzoyl)-4-hydroxy-2-propyl-pyrrolidine-1-carboxylic acid tert-butyl esterHCID 66687330—

반응 단계

(R)-2-(3,4-Dichloro-benzoyl)-4-hydroxy-2-propyl-pyrrolidine-1-carboxylic acid tert-butyl ester was prepared by treating (R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-propyl-2-(3,4-dichloro-benzoyl)-pyrrolidine-1-carboxylic acid tert-butyl ester with TMAF following the procedure of step 3 of Example 11.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08084623B2
출처 데이터셋uspto-grants-2011_12
ORD IDord-b2754af559cd48a8b65f0ac3684c5f71
출처 메모uspto-grants-2011_12