1-Bromo-2-methylpropane → Tert-butyl 2-(2-((1-isobutylpiperidine-4-yl)(methyl)amino)-2-oxoethoxy)-4,6-dimethylpyrimidine-5-ylcarbamate

반응식

[CH2:29]([CH:30]([CH3:31])[CH3:32])[Br:33].[CH3:1][c:2]1[n:3][c:4]([O:17][CH2:18][C:19](=[O:20])[N:21]([CH:22]2[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]2)[CH3:28])[n:5][c:6]([CH3:16])[c:7]1[NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15]>>[CH3:1][c:2]1[n:3][c:4]([O:17][CH2:18][C:19](=[O:20])[N:21]([CH:22]2[CH2:23][CH2:24][N:25]([CH2:29][CH:30]([CH3:31])[CH3:32])[CH2:26][CH2:27]2)[CH3:28])[n:5][c:6]([CH3:16])[c:7]1[NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15]

참가 물질

반응물 2

HCID 65551-Bromo-2-methylpropane

HCID 59336171Tert-butyl 4,6-dimethyl-2-(2-(methyl(piperidine-4-yl)amino)-2-oxoethoxy)pyrimidine-5-ylcarbamate

생성물 1

HCID 68416124Tert-butyl 2-(2-((1-isobutylpiperidine-4-yl)(methyl)amino)-2-oxoethoxy)-4,6-dimethylpyrimidine-5-ylcarbamate

출처 및 근거

ORD 기록: ord-64f4b7f4583c44c997660fcb2bfb7647
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

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