Selenium Dioxide → 2-Methoxyphenylglyoxal hydrate
반응식
C[O:2][CH2:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:5].[Se](=O)=O.[O:15]1CCOC[CH2:16]1>O.C(OCC)(=O)C>[OH2:2].[CH3:16][O:15][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[C:4]([CH:3]=[O:2])=[O:5]참가 물질
6
실험 절차
3 g of 2-methoxyacetophenone are dissolved in 15 ml of dioxane, and a solution of 3.3 g of selenium dioxide in 1.5 ml of water is added thereto. The solution is refluxed for 15 hours. After the reaction, insoluble materials are removed by filtration, and the filtrate is concentrated. The oily residue thus obtained is dissolved in ethyl acetate. The ethyl acetate solution is washed with water and then with an aqueous sodium bicarbonate solution and water. Then, said solution is dried and evaporated to remove solvent. 3.1 g of 2-methoxyphenylglyoxal hydrate are obtained as a crude oil.
후처리
- temperatureThe solution is refluxed for 15 hours
- customAfter the reaction, insoluble materials
- customare removed by filtration
- concentrationthe filtrate is concentrated
- customThe oily residue thus obtained
- washThe ethyl acetate solution is washed with water
- customis dried
- customevaporated
- customto remove solvent
출처 및 근거
- ORD 기록
- ord-d7ae0d83b4204e4da29186e8c627e9d9
- 출처 데이터셋
- uspto-grants-1978_12
- 특허 번호
- US04131686
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