6-Methyl-2-nitropyridin-3-ol → 2-Amino-6-methylpyridin-3-ol

HRID 66354

반응식

HRID 66354 반응식
[OH:1][C:2]1[C:3]([N+:9]([O-])=O)=[N:4][C:5]([CH3:8])=[CH:6][CH:7]=1>[Pd].CO>[NH2:9][C:3]1[C:2]([OH:1])=[CH:7][CH:6]=[C:5]([CH3:8])[N:4]=1

참가 물질

4

반응물 1

HCID 848016-Methyl-2-nitropyridin-3-ol

생성물 1

HCID 885002-Amino-6-methylpyridin-3-ol

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

3-Hydroxy-6-methyl-2-nitropyridine (3.5 g.) in 75 ml. of methanol was reduced over 1 g. of 5% palladium-on-carbon catalyst. The catalyst was removed by filtration and the filtrate was concentrated to dryness to give 2-amino-3-hydroxy-6-methylpyridine which was used directly in the next step.

후처리

  1. customThe catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated to dryness

출처 및 근거

ORD 기록
ord-4289872c8b854b6d8388299f54433d7b
출처 데이터셋
uspto-grants-1978_12
특허 번호
US04131677

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