6-Methyl-2-nitropyridin-3-ol → 2-Amino-6-methylpyridin-3-ol
반응식
[OH:1][C:2]1[C:3]([N+:9]([O-])=O)=[N:4][C:5]([CH3:8])=[CH:6][CH:7]=1>[Pd].CO>[NH2:9][C:3]1[C:2]([OH:1])=[CH:7][CH:6]=[C:5]([CH3:8])[N:4]=1참가 물질
4
실험 절차
3-Hydroxy-6-methyl-2-nitropyridine (3.5 g.) in 75 ml. of methanol was reduced over 1 g. of 5% palladium-on-carbon catalyst. The catalyst was removed by filtration and the filtrate was concentrated to dryness to give 2-amino-3-hydroxy-6-methylpyridine which was used directly in the next step.
후처리
- customThe catalyst was removed by filtration
- concentrationthe filtrate was concentrated to dryness
출처 및 근거
- ORD 기록
- ord-4289872c8b854b6d8388299f54433d7b
- 출처 데이터셋
- uspto-grants-1978_12
- 특허 번호
- US04131677
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