5-bromo-N-(1,3-dihydroxy-2-methylpropan-2-yl)pyridine-3-sulfonamide → 5-[5-(3,4-Dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridine-3-sulfonic acid (2-hydroxy-1-hydroxymethyl-1-methyl-ethyl)-amide

반응식

[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]3[n:12]([c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[n:19][cH:20][c:21]3[C:22]#[CH:23])[cH:5][cH:6][c:7]1[Cl:8].[OH:24][CH2:25][C:26]([CH3:27])([CH2:28][OH:29])[NH:30][S:31](=[O:32])(=[O:33])[c:34]1[cH:35][n:36][cH:37][c:38]([Br:40])[cH:39]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]3[n:12]([c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[n:19][cH:20][c:21]3[C:22]#[C:23][c:38]2[cH:37][n:36][cH:35][c:34]([S:31]([NH:30][C:26]([CH2:25][OH:24])([CH3:27])[CH2:28][OH:29])(=[O:32])=[O:33])[cH:39]2)[cH:5][cH:6][c:7]1[Cl:8]