Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Imidazole → Trimethyl[(oct-1-yn-4-yl)oxy]silane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Imidazole | HCID 795 | — |
| 반응물 | Chlorotrimethylsilane | HCID 6397 | — |
| 반응물 | 1-Octyn-4-ol | HCID 103656 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Trimethyl[(oct-1-yn-4-yl)oxy]silane | HCID 12786181 | — |
반응 단계
To a cold solution of 166 g of 4-hydroxy-1-octyne [Prostaglandins, 10, 289 (1975)] , and 240 g of imidazole in one liter of dimethylformamide is added dropwise 202 g of chlorotrimethylsilane. The mixture is allowed to stand at room temperature for 2 to 3 days. The mixture is partitioned with water and hexane. The hexane layer is washed with brine, dried over magnesium sulfate, and concentrated. Distillation of the residue gives a colorless liquid, b.p. 38° (0.2mm).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04131737 |
| 출처 데이터셋 | uspto-grants-1978_12 |
| ORD ID | ord-3568b4a541224a9686c22814bb253b2e |
| 출처 메모 | uspto-grants-1978_12 |