Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-(1-Methyl-2-pyrrolylcarbonyl)propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ethyl Acrylate | HCID 8821 | — |
| 반응물 | 1-Methyl-1H-pyrrole-2-carbaldehyde | HCID 14504 | — |
| 반응물 | (1-methyl-1H-pyrrol-2-yl)(morpholin-4-yl)acetonitrile | HCID 20529962 | — |
| 생성물 | 3-(1-Methyl-2-pyrrolylcarbonyl)propionic acid | HCID 12504054 | — |
반응 단계
As for Example 6, 1-methyl-2-pyrrolecarboxaldehyde is converted to α-(1-methyl-2-pyrrolyl)-4-morpholineacetonitrile. The preceding compound is reacted with ethyl acrylate and the resulting 1,4-addition product is heated at 100° C. with 6 N hydrochloric acid to give 3-(1-methyl-2-pyrrolylcarbonyl)propionic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04342689 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-ed70aec0f2b745ecb50641d333fc415f |
| 출처 메모 | uspto-grants-1982_08 |