Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine N-Oxide → Pyridine N-Oxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine N-Oxide | HCID 12753 | — |
| 반응물 | L-Proline | HCID 145742 | — |
| 반응물 | 4-Oxo-4-(2-pyridyl)butyric acid | HCID 2760269 | — |
| 생성물 | Pyridine N-Oxide | HCID 12753 | — |
| 생성물 | 1-[3-(2-pyridylcarbonyl)propionyl]-L-proline | HCID 54135146 | — |
반응 단계
As for Example 11, γ-oxo-2-pyridinebutyric acid, pyridine-1-oxide is coupled to L-proline to give 1-[3-(2-pyridylcarbonyl)propionyl]-L-proline, pyridine-1-oxide. Reaction of the preceding compound with bromine in acetic acid and reaction of the brominated compound with sodium thioacetate in acetonitrile gives the product of the Example as a glass.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04342691 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-d1b93664865944cd9e1b8499dc1504f6 |
| 출처 메모 | uspto-grants-1982_08 |