Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → alpha-[(6-Acetyl-2-methoxycarbonylphenyl)oxy]-gamma-butyrolactone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2(3H)-Furanone, 3-bromodihydro- | HCID 95463 | — |
| 반응물 | Methyl 3-acetyl-2-hydroxybenzoate | HCID 13037297 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | alpha-[(6-Acetyl-2-methoxycarbonylphenyl)oxy]-gamma-butyrolactone | HCID 13037298 | — |
반응 단계
To a mixture of methyl 3-acetylsalicylate (5.8 g) and potassium carbonate (10.4 g) in acetone (200 ml) was added α-bromo-γ-butyrolactone (12.5 g) under stirring, and the mixture was refluxed for 11 hours. The insolubles were filtered off and the filtrate was concentrated under reduced pressure. The residue was subjected to chromatography on silica gel eluting with chloroform. By the above procedure, there was obtained α-[(6-acetyl-2-methoxycarbonylphenyl)oxy]-γ-butyrolactone as pale yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04342779 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-6d6d16c133d14dc98d2670831a546e4a |
| 출처 메모 | uspto-grants-1982_08 |