1-(2-Chloroethyl)pyrrolidine hydrochloride → 1-{2-Chloro-4-[2-(N-pyrrolidinyl)ethoxy]-phenyl}-1-butanone
반응식
[Cl:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][CH2:10][N:11]([CH2:14][CH3:15])[CH2:12][CH3:13])[CH:5]=[CH:4][C:3]=1[C:16](=[O:20])[CH2:17][CH2:18][CH3:19].Cl.ClCCN1CCCC1>>[Cl:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][CH2:10][N:11]2[CH2:12][CH2:13][CH2:15][CH2:14]2)[CH:5]=[CH:4][C:3]=1[C:16](=[O:20])[CH2:17][CH2:18][CH3:19]참가 물질
3
실험 절차
This compound is prepared by essentially the same procedure as described in Example 1 Step A except that the 2-diethylaminoethyl chloride hydrochloride of Example 1 Step A is replaced by an equimolecular quantity of N-(2-chloroethyl)pyrrolidine hydrochloride. The product is obtained as a pale yellow oil upon distillation in vacuo (0.3 mm.).
후처리
- customThis compound is prepared by essentially the same procedure
- customThe product is obtained as a pale yellow oil upon distillation in vacuo (0.3 mm.)
출처 및 근거
- ORD 기록
- ord-3b2fef9249ba4fb9b8c9f123edf9d8cb
- 출처 데이터셋
- uspto-grants-1982_08
- 특허 번호
- US04342782
반응 노트
불러오는 중…