Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl Sulfoxide → 2-(4-Chlorophenoxy)acetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | 4-Chlorophenol | HCID 4684 | — |
| 반응물 | Chloroacetonitrile | HCID 7856 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-(4-Chlorophenoxy)acetonitrile | HCID 306444 | 92.5% |
반응 단계
A mixture of 64.25 g of 4-chlorophenol, 98 g of anhydrous potassium carbonate, 40 g of chloroacetonitrile and 100 ml of dimethyl sulfoxide was heated with stirring in a 500 ml round-bottomed three-necked flask at 70°-80° C. for 3.0 hours. The reaction mixture was then poured into ice and water. After the ice melted, the mixture was filtered and the product washed well with water which gave 77.5 g of 4-chlorophenoxyacetonitrile.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04343809 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-9c18c5a5f562428fb1f2d2a6984cc88c |
| 출처 메모 | uspto-grants-1982_08 |