Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Alcohol → 2-(Benzyloxy)-3-chloropyrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Alcohol | HCID 244 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2,3-Dichloropyrazine | HCID 78575 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 2-(Benzyloxy)-3-chloropyrazine | HCID 20528929 | — |
반응 단계
Sodium hydride (0.10 mole) is added to 0.10 mole of benzyl alcohol in 100 ml. dry benzene and the mixture is refluxed 1-2 hours. The cooled solution is treated with 0.10 mole of 2,3-dichloropyrazine in 100 ml. of benzene. The mixture is refluxed for 20-60 hours, cooled, washed with water, dried, and evaporated and the product distilled in vacuo to give 2-chloro-3-benzyloxypyrazine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04343802 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-225288ec1c894972937e9a596b5c7a79 |
| 출처 메모 | uspto-grants-1982_08 |