Ethanol → HCID 309391, 화합물
반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]([CH3:17])=[CH:11][C:12]([O:14]CC)=[O:13])=[CH:6][CH:5]=1)([O-:3])=[O:2].C(O)C.[OH-].[K+].O>C(OCC)(=O)C>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([C:10]([CH3:17])=[CH:11][C:12]([OH:14])=[O:13])=[CH:8][CH:9]=1)([O-:3])=[O:2]참가 물질
6
실험 절차
A mixture of 16.6 g. of ethyl 3-(4-nitrophenyl)-2-butenoate, 75 ml. of ethanol and 94.7 ml. of 1.5 N potassium hydroxide was heated on a steam bath for 70 minutes, and then it was cooled to room temperature. To the reaction mixture was added 200 ml. of water and 200 ml. of ethyl acetate. The aqueous phase was removed and acidified with concentrated hydrochloric acid, and then the solid was recovered by filtration. This latter solid was recrystallized from aqueous ethanol to give 9.8 g. (67% yield) of the title compound, m.p. 167°-169° C.
후처리
- additionA mixture of 16.6 g
- additionTo the reaction mixture was added 200 ml
- customThe aqueous phase was removed
- filtrationthe solid was recovered by filtration
- customThis latter solid was recrystallized from aqueous ethanol
- customto give 9.8 g
출처 및 근거
- ORD 기록
- ord-d6d944dfea2245e5af1a612c24b763b8
- 출처 데이터셋
- uspto-grants-1982_08
- 특허 번호
- US04343813
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