Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Bromide → 5-benzyloxy-3-phenyl-1H-2-indole-carboxylic acid ethylester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Bromide | HCID 7498 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Ethyl 5-hydroxy-3-phenyl-1H-indole-2-carboxylate | HCID 11550917 | — |
| 용매 | Methyl Ethyl Ketone | HCID 6569 | — |
| 생성물 | 5-benzyloxy-3-phenyl-1H-2-indole-carboxylic acid ethylester | HCID 4777862 | — |
반응 단계
Twenty-six grams (92.4 m mole) of 5-hydroxy-3-phenyl-1H-2-indole carboxylic acid ethylester were refluxed for four days with 27.6 g of potassium carbonate and 11 ml (92.4 mole) of benzylbromide in 700 ml of methyl-ethylketone. After filtration and evaporation, the residue was chromatographed on silicagel (solvent: toluene).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04343811 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-0cfe56dcc81144c48b41a140a5ebcfd0 |
| 출처 메모 | uspto-grants-1982_08 |