Propanoic acid, 2-bromo-2-methyl-, ethyl ester → 2-[1-Isobutyl-2-methyl-3-(4-pyridyl)-1H-indole-5-yloxy]-2-methyl-propanoic acid ethylester

HRID 66862노트

반응식

HRID 66862 반응식
[CH2:1]([N:5]1[C:13]2[C:8](=[CH:9][C:10]([OH:14])=[CH:11][CH:12]=2)[C:7]([C:15]2[CH:20]=[CH:19][N:18]=[CH:17][CH:16]=2)=[C:6]1[CH3:21])[CH:2]([CH3:4])[CH3:3].[CH2:22]([O:24][C:25](=[O:30])[C:26](Br)([CH3:28])[CH3:27])[CH3:23]>>[CH2:22]([O:24][C:25](=[O:30])[C:26]([O:14][C:10]1[CH:9]=[C:8]2[C:13](=[CH:12][CH:11]=1)[N:5]([CH2:1][CH:2]([CH3:4])[CH3:3])[C:6]([CH3:21])=[C:7]2[C:15]1[CH:16]=[CH:17][N:18]=[CH:19][CH:20]=1)([CH3:28])[CH3:27])[CH3:23]

참가 물질

3

반응물 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 205291211-isobutyl-2-methyl-3-(4-pyridyl)-1H-indole-5-ol

생성물 1

HCID 543266782-[1-Isobutyl-2-methyl-3-(4-pyridyl)-1H-indole-5-yloxy]-2-methyl-propanoic acid ethylester

실험 절차

The above compound was prepared from 1-isobutyl-2-methyl-3-(4-pyridyl)-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10.

출처 및 근거

ORD 기록
ord-1842db152e054ea29713d76eb65302a7
출처 데이터셋
uspto-grants-1982_08
특허 번호
US04343811

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