Morpholine → 2-Methyl-2-[2-Methyl-1-propyl-3-(4-pyridyl)-1H-indole-5-yloxy]-propanoic acid morpholide
반응식
Cl.[CH3:2][C:3]([O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[N:14]([CH2:18][CH2:19][CH3:20])[C:13]([CH3:21])=[C:12]2[C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1)([CH3:7])[C:4]([OH:6])=O.[NH:28]1[CH2:33][CH2:32][O:31][CH2:30][CH2:29]1>>[CH3:7][C:3]([O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[N:14]([CH2:18][CH2:19][CH3:20])[C:13]([CH3:21])=[C:12]2[C:22]1[CH:23]=[CH:24][N:25]=[CH:26][CH:27]=1)([CH3:2])[C:4]([N:28]1[CH2:33][CH2:32][O:31][CH2:30][CH2:29]1)=[O:6]참가 물질
3
실험 절차
The above compound was prepared from 2-methyl-2-[2-methyl-1-propyl-3-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid hydrochloride and morpholine using a procedure analogous to that of Example 128.
출처 및 근거
- ORD 기록
- ord-5f73bc3d005c4034aec067d4570eedc8
- 출처 데이터셋
- uspto-grants-1982_08