Methylamine → 2-Methyl-2-[2-methyl-1-propyl-3-(4-pyridyl)-1H-indole-5-yloxy]-propanoic acid methylamide

HRID 66916노트

반응식

HRID 66916 반응식
Cl.[CH3:2][C:3]([O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[N:14]([CH2:18][CH2:19][CH3:20])[C:13]([CH3:21])=[C:12]2[C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1)([CH3:7])[C:4]([OH:6])=O.[CH3:28][NH2:29]>O1CCOCC1>[CH3:28][NH:29][C:4](=[O:6])[C:3]([CH3:7])([O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[N:14]([CH2:18][CH2:19][CH3:20])[C:13]([CH3:21])=[C:12]2[C:22]1[CH:27]=[CH:26][N:25]=[CH:24][CH:23]=1)[CH3:2]

참가 물질

4

반응물 2

HCID 6329MethylamineHCID 3059433Propanoic acid, 2-methyl-2-((2-methyl-1-propyl-3-(4-pyridinyl)-1H-indol-5-yl)oxy)-, hydrochloride

생성물 1

HCID 540302722-Methyl-2-[2-methyl-1-propyl-3-(4-pyridyl)-1H-indole-5-yloxy]-propanoic acid methylamide

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

The above compound was prepared from 2-methyl-2-[2-methyl-1-propyl-3-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid hydrochloride and methylamine in dioxane using a procedure analogous to that of Example 128.

출처 및 근거

ORD 기록
ord-ec65866c75be4f978567e4f78a8a1742
출처 데이터셋
uspto-grants-1982_08
특허 번호
US04343811

반응 노트

불러오는 중…