Acetonitrile → Tert-butyl 2-[(3-amino-7-bromo[1,5]naphthyridin-4-yl)amino]-1,1-dimethylethylcarbamate

반응식

[Br:25][c:26]1[cH:27][n:28][c:29]2[c:30]([NH:39][CH2:40][C:41]([CH3:42])([CH3:43])[NH:44][C:45]([O:46][C:47]([CH3:48])([CH3:49])[CH3:50])=[O:51])[c:31]([N+:36]([O-:37])=[O:38])[cH:32][n:33][c:34]2[cH:35]1.[CH3:52][C:53]#[N:54].[NH2:1][c:2]1[c:3]2[n:4][c:5]([CH2:6][O:7][CH2:8][CH3:9])[n:10]([CH2:11][C:12]([CH3:13])([OH:14])[CH3:15])[c:16]2[c:17]2[n:18][cH:19][c:20]([Br:21])[cH:22][c:23]2[n:24]1>>[Br:25][c:26]1[cH:27][n:28][c:29]2[c:30]([NH:39][CH2:40][C:41]([CH3:42])([CH3:43])[NH:44][C:45]([O:46][C:47]([CH3:48])([CH3:49])[CH3:50])=[O:51])[c:31]([NH2:36])[cH:32][n:33][c:34]2[cH:35]1