Sulfuric Acid → 3,4-Difluoroaniline

반응식

[F:1][C:2]1[CH:3]=[C:4]([NH2:12])[C:5](=[CH:9][C:10]=1[F:11])C(O)=O.S(=O)(=O)(O)O>>[F:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:9][C:10]=1[F:11])[NH2:12]

참가 물질

반응물 2

HCID 1118Sulfuric Acid

HCID 7359652-Amino-4,5-difluorobenzoic acid

생성물 1

HCID 774693,4-Difluoroaniline

실험 절차

Following the procedure of Example 1B, the 4,5-difluoroanthranilic acid was decarboxylated by reaction with sulfuric acid, to form 3,4-difluoroaniline.

출처 및 근거

ORD 기록: ord-cc734f5572d84685a451386a210172d7
출처 데이터셋: uspto-grants-1982_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04343951

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