Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodine → 5,5-Dimethyl-1-iodo-trans-octen-3-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodine | HCID 807 | — |
| 반응물 | Trimethylamine oxide | HCID 1145 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Bis(1,2-dimethylpropyl)borane | HCID 192733 | — |
| 반응물 | 5,5-Dimethyl-3-tetrahydropyranyloxy-1-octyne | HCID 53889730 | — |
| 반응물 | Tetrahydrofuranacetic acid water | HCID 86732972 | — |
| 용매 | Diglyme | HCID 8150 | — |
| 생성물 | 5,5-Dimethyl-1-iodo-trans-octen-3-ol | HCID 20465606 | — |
반응 단계
Treatment of 23.8 g. (0.100 mole) of 5,5-dimethyl-3-tetrahydropyranyloxy-1-octyne (Example 999) successively with 233 ml. of 0.43 M disiamylborane in diglyme, 22.5 g. of trimethylamine oxide, 150 ml. of 1 N sodium hydroxide, 25.4 g. of iodine, and 900 ml. of 3:1:1 tetrahydrofuranacetic acid-water as described in Example 996 gives the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04343949 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-f75259f3d49b43d6acb4b73ba456781c |
| 출처 메모 | uspto-grants-1982_08 |