1-Cyclohexyl-2-imidazolidinone → 3-Cyclohexyl-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-2-oxoimidazolidine-1-carboxamide

반응식

[CH:39]1([N:45]2[CH2:46][CH2:47][NH:48][C:49]2=[O:50])[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44]1.[F:1][c:2]1[cH:3][c:4]([NH:24][C:25](=[O:26])[N:27]2[C:28](=[O:38])[N:29]([N:32]3[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]3)[CH2:30][CH2:31]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[n:19][cH:20][n:21]([CH3:23])[cH:22]1)[s:17]2>>[F:1][c:2]1[cH:3][c:4]([NH:24][C:25](=[O:26])[N:27]2[C:28](=[O:38])[N:29]([CH:39]3[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44]3)[CH2:30][CH2:31]2)[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16](-[c:18]1[n:19][cH:20][n:21]([CH3:23])[cH:22]1)[s:17]2

참가 물질

반응물 2

HCID 5803521-Cyclohexyl-2-imidazolidinone

HCID 58790362N-(3-Fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-2-oxo-3-(piperidin-1-yl)imidazolidine-1-carboxamide

생성물 1

HCID 587900743-Cyclohexyl-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-2-oxoimidazolidine-1-carboxamide

출처 및 근거

ORD 기록: ord-89fd62ca2f174989b60cc87990391092
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

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