Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
O-Cresol → 4-Chloro-2-methylphenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | O-Cresol | HCID 335 | — |
| 반응물 | Sulfuryl chloride | HCID 24648 | — |
| 생성물 | 4-Chloro-2-methylphenol | HCID 14855 | 84% |
반응 단계
The chlorination of aromatic compounds with sulfuryl chloride is generally known. For example, DuBois in Z. F. Chem. 705 (1866) reported that treatment of molten phenol with an equal molar amount of sulfuryl chloride yields only p-chlorophenol. Sulfuryl chloride was first reported as a chlorinating agent for o-cresol by Sah and Anderson in J. Am. Chem. Soc. 63, 3164 (1941). Their data showed that o-cresol reacted with sulfuryl chloride to yield 84% of the 4-chloro-o-cresol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04345097 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-6de4de661824448bb1353af245631ff8 |
| 출처 메모 | uspto-grants-1982_08 |