Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isopropanol → 2,3,5,6,7,8-Hexahydro-2,3-diphenylthiazolo[3,2-a][1,3]-diazepin-3-ol L-tartrate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | L-Tartaric acid | HCID 444305 | — |
| 반응물 | 2,3,5,6,7,8-Hexahydro-2,3-diphenylthiazolo[3,2-a][1,3]diazepin-3-ol | HCID 13068289 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 2,3,5,6,7,8-Hexahydro-2,3-diphenylthiazolo[3,2-a][1,3]-diazepin-3-ol L-tartrate | HCID 70551165 | — |
반응 단계
A solution of 3.42 g. of 2,3,5,6,7,8-hexahydro-2,3-diphenylthiazolo[3,2-a][1,3]diazepin-3-ol, prepared as described in Example 4, in acetone is treated with a solution of 1.50 g. of L-tartaric acid in acetone. Isopropanol is added and the mixture is warmed briefly to dissolve the gum which forms. After cooling, the solid is collected and recrystallized from a mixture of methanol and isopropanol, giving 3.15 g. of the desired product, m.p. 138°-140° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04344954 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-6b200dc4c9e34ec8ad8e447a85ed3847 |
| 출처 메모 | uspto-grants-1982_08 |