Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 6-Methyl-4-oxo-1-phenyl-1,4-dihydropyridazine-3-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Aniline | HCID 6115 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Benzenediazonium chloride | HCID 60992 | — |
| 반응물 | 2H-Pyran-2-one | HCID 68154 | — |
| 반응물 | Sodium Nitrite | HCID 23668193 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 6-Methyl-4-oxo-1-phenyl-1,4-dihydropyridazine-3-carboxylic acid | HCID 2784470 | — |
반응 단계
In a separate flask; 9.08 g of aniline is mixed with 37.5 ml of concentrated hydrochloric acid and 47 ml of water. The resulting solution is maintained at about 5° to 10° and a solution of 7.13 g of sodium nitrite in 24 ml of water is added. The resulting solution of phenyldiazonium chloride is added dropwise to the stirred pyrone solution, while maintaining a temperature of about 5° to 10°. The pH is maintained at about 8 to 9 by the addition of small amounts of sodium hydroxide solution.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04345934 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-915b1bca08b5473ca1be8ff56feb7a55 |
| 출처 메모 | uspto-grants-1982_08 |