2-Amino-N,2-dimethylpropanamide → 6-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid (1-methyl-1-methylcarbamoyl-ethyl)-amide

HRID 673196노트

반응식

HRID 673196 반응식
[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:20])([F:21])[CH2:18][CH2:19]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1.[NH2:22][C:23]([C:24](=[O:25])[NH:26][CH3:27])([CH3:28])[CH3:29]>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:20])([F:21])[CH2:18][CH2:19]3)[cH:8][cH:9][c:10]([C:12](=[O:14])[NH:22][C:23]([C:24](=[O:25])[NH:26][CH3:27])([CH3:28])[CH3:29])[n:11]2)[CH2:2][CH2:3]1

참가 물질

3

반응물 2

HCID 187922142-Amino-N,2-dimethylpropanamideHCID 710877506-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid

생성물 1

HCID 710936136-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid (1-methyl-1-methylcarbamoyl-ethyl)-amide

출처 및 근거

ORD 기록
ord-c1b190e6588643cc8b0373af729f2e60
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

반응 노트

불러오는 중…