Dimethylformamide → 4-(4-(2-Carbamoylpyridin-4-yloxy)-3-fluorophenylamino)-2-cyano-N-(2,4-difluorophenyl)pyrimidine-5-carboxamide

반응식

[C:1]([NH2:2])(=[O:3])[c:4]1[n:5][cH:6][cH:7][c:8]([O:10][c:11]2[c:12]([F:39])[cH:13][c:14]([NH:17][c:18]3[n:19][c:20]([S:35]([CH3:36])(=[O:37])=[O:38])[n:21][cH:22][c:23]3[C:24](=[O:25])[NH:26][c:27]3[c:28]([F:34])[cH:29][c:30]([F:33])[cH:31][cH:32]3)[cH:15][cH:16]2)[cH:9]1.[K:40][C:41]#[N:42].[O:43]=[CH:44][N:45]([CH3:46])[CH3:47]>>[C:1]([NH2:2])(=[O:3])[c:4]1[n:5][cH:6][cH:7][c:8]([O:10][c:11]2[c:12]([F:39])[cH:13][c:14]([NH:17][c:18]3[n:19][c:20]([C:41]#[N:42])[n:21][cH:22][c:23]3[C:24](=[O:25])[NH:26][c:27]3[c:28]([F:34])[cH:29][c:30]([F:33])[cH:31][cH:32]3)[cH:15][cH:16]2)[cH:9]1