Dimethylformamide → 7-chloro-3-(5-diisopropylaminomethyl-1,2,4-oxadiazol-3-yl)-5-methyl-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one

반응식

[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[CH:25]([CH3:26])([CH3:27])[NH:28][CH:29]([CH3:30])[CH3:31].[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:24])[N:9]([CH3:23])[CH2:10][c:11]1[n:12]-2[cH:13][n:14][c:15]1-[c:16]1[n:17][o:18][c:19]([CH2:21][Cl:22])[n:20]1>>[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:24])[N:9]([CH3:23])[CH2:10][c:11]1[n:12]-2[cH:13][n:14][c:15]1-[c:16]1[n:17][o:18][c:19]([CH2:21][N:28]([CH:25]([CH3:26])[CH3:27])[CH:29]([CH3:30])[CH3:31])[n:20]1

참가 물질

반응물 3

HCID 6228Dimethylformamide

HCID 7912Diisopropylamine

HCID 224621917-Chloro-3-(5-chloromethyl-[1,2,4]oxadiazol-3-yl)-5-methyl-4,5-dihydro-imidazo[1,5-a][1,4]benzodiazepin-6-one

생성물 1

HCID 229145077-chloro-3-(5-diisopropylaminomethyl-1,2,4-oxadiazol-3-yl)-5-methyl-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one

출처 및 근거

ORD 기록: ord-43cdc848d3c146e7952e1a2258c48bf4
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…