Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → (5-methoxy-4-methyl-1H-indol-3-ylmethyl)dimethylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Dimethylamine | HCID 674 | — |
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | 5-Methoxy-4-methylindole | HCID 3296242 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | (5-methoxy-4-methyl-1H-indol-3-ylmethyl)dimethylamine | HCID 22018474 | — |
반응 단계
Acetic acid (0.39 mL) and dimethylamine (0.85 mL of a 40% aqueous solution) were added to a suspension of paraformaldehyde (0.21 g) in 25 mL ethanol. The mixture was heated to reflux until it was clear. The solution was cooled to rt and a solution of 5-methoxy-4-methyl-indole (1.0 g) in 25 mL of ethanol was added. The reaction was heated to reflux for 3 h. The volatiles were removed in vacuo to yield (5-methoxy-4-methyl-1H-indol-3-ylmethyl)-dimethylamine (1.0 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07084154B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-cb0d67a099774221b16872d3e7d1a7ba |
| 출처 메모 | uspto-grants-2006_08 |