3-(Bromomethyl)-1H-indazole, N1-BOC protected → 3-{6-[(benzyl-isopropyl-carbamoyl)-methyl]-8,9-difluoro-5-oxo-1-phenyl-5,6-dihydro-4H-2,3,6,10b-tetraaza-benzo[e]azulen-4-ylmethyl}-indazole-1-carboxylic acid tert-butyl ester

반응식

[C:38]([CH3:39])([CH3:40])([CH3:41])[O:42][C:43](=[O:44])[n:45]1[n:46][c:47]([CH2:54][Br:55])[c:48]2[cH:49][cH:50][cH:51][cH:52][c:53]12.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([C:9]([CH2:10][N:11]1[c:12]2[c:13]([cH:28][c:29]([F:33])[c:30]([F:32])[cH:31]2)-[n:14]2[c:15](-[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[n:16][n:17][c:18]2[CH2:19][C:20]1=[O:21])=[O:34])[CH:35]([CH3:36])[CH3:37]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([C:9]([CH2:10][N:11]1[c:12]2[c:13]([cH:28][c:29]([F:33])[c:30]([F:32])[cH:31]2)-[n:14]2[c:15](-[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[n:16][n:17][c:18]2[CH:19]([CH2:54][c:47]2[n:46][n:45]([C:43]([O:42][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:44])[c:53]3[c:48]2[cH:49][cH:50][cH:51][cH:52]3)[C:20]1=[O:21])=[O:34])[CH:35]([CH3:36])[CH3:37]