Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(+-)-p-Methoxyamphetamine → 1-(p-Methoxyphenyl)-2-propanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (+-)-p-Methoxyamphetamine | HCID 31721 | — |
| 반응물 | 3-Methyl-1,2,3,4-tetrahydroisoquinolin-7-ol | HCID 22018519 | — |
| 생성물 | 1-(p-Methoxyphenyl)-2-propanone | HCID 31231 | — |
| 생성물 | 7-Methoxy-1,2,3,4-Tetrahydroisoquinoline | HCID 417288 | — |
| 생성물 | 1,2,3,4-Tetrahydroisoquinolin-7-ol | HCID 419268 | — |
반응 단계
7-Methoxy-1,2,3,4-tetrahydro-isoquinoline and 1,2,3,4-tetrahydro-isoquinolin-7-ol were prepared by a literature procedure (J. Med. Chem. 1987, 30, 2208–2216). 2-(4-Methoxy-phenyl)-1-methyl-ethylamine required for the preparation of 3-methyl-1,2,3,4-tetrahydro-isoquinolin-7-ol was obtained from 1-(4-methoxy-phenyl)-propan-2-one by Procedure X and was subsequently converted to the tetrahydroisoquinoline by the same literature method.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07084154B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-f405ed59b2104cc7a767f0e2836109f2 |
| 출처 메모 | uspto-grants-2006_08 |