Phosgene → HCID 178484191, 화합물

HRID 67785

반응식

HRID 67785 반응식
C(Cl)([Cl:3])=O.O1CCCC1.[CH3:10][NH:11][C:12]([NH:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=S>CN(C)C=O>[ClH:3].[CH3:10][NH:11][C:12]([Cl:3])=[N:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

참가 물질

5

반응물 3

HCID 6371Phosgene2회HCID 8028TetrahydrofuranHCID 6982941-Methyl-3-phenylthiourea

생성물 1

HCID 178484191HCID 178484191, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

After passing 6.3 g of phosgene into 40 ml of absolute tetrahydrofuran at room temperature, 8 g of 1-methyl-3-phenylthiourea are added, with stirring, the color of the suspension changing instantaneously to yellow. After adding 0.5 ml of dimethylformamide, the mixture is stirred for 20 hours at room temperature, nitrogen is then passed through the reaction mixture for about 30 minutes, in order to drive off the phosgene, and the crystals are filtered off and washed with tetrahydrofuran. Crystals with a melting point of 169° C. (with decomposition).

후처리

  1. customat room temperature
  2. stirringthe mixture is stirred for 20 hours at room temperature
  3. filtrationthe crystals are filtered off
  4. washwashed with tetrahydrofuran

출처 및 근거

ORD 기록
ord-0f79ccd029194271bff947b0b7abc7ea
출처 데이터셋
uspto-grants-1982_08
특허 번호
US04346088

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