4'-Hydroxy-4-biphenylcarbonitrile → 1-(4-Chloro-benzoyl)-3-(4'-cyano-biphenyl-4-yloxymethyl)-pyrrolidine-3-carboxylic acid ethyl ester

반응식

[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1([CH2:20][I:21])[CH2:7][N:8]([C:11]([c:12]2[cH:13][cH:14][c:15]([Cl:18])[cH:16][cH:17]2)=[O:19])[CH2:9][CH2:10]1.[OH:22][c:23]1[cH:24][cH:25][c:26](-[c:29]2[cH:30][cH:31][c:32]([C:35]#[N:36])[cH:33][cH:34]2)[cH:27][cH:28]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[C:6]1([CH2:20][O:22][c:23]2[cH:24][cH:25][c:26](-[c:29]3[cH:30][cH:31][c:32]([C:35]#[N:36])[cH:33][cH:34]3)[cH:27][cH:28]2)[CH2:7][N:8]([C:11]([c:12]2[cH:13][cH:14][c:15]([Cl:18])[cH:16][cH:17]2)=[O:19])[CH2:9][CH2:10]1

참가 물질

반응물 2

HCID 1406104'-Hydroxy-4-biphenylcarbonitrile

HCID 593221801-(4-Chloro-benzoyl)-3-iodomethyl-pyrrolidine-3-carboxylic acid ethyl ester

생성물 1

HCID 593222341-(4-Chloro-benzoyl)-3-(4'-cyano-biphenyl-4-yloxymethyl)-pyrrolidine-3-carboxylic acid ethyl ester

출처 및 근거

ORD 기록: ord-26b5a40782374d048086a1dbf7f53a28
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…