Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Chlorobenzoic Acid → Thionyl Chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Chlorobenzoic Acid | HCID 447 | — |
| 반응물 | 2-Amino-2-methyl-1-propanol | HCID 11807 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | Benzoyl chloride, 3-chloro- | HCID 69252 | — |
| 생성물 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | Oxazole, 2-(3-chlorophenyl)-4,5-dihydro-4,4-dimethyl- | HCID 10798476 | — |
반응 단계
2-(3-Chlorophenyl)-4,4-dimethyl-2-oxazoline was prepared from 3-chlorobenzoic acid by reaction with thionyl chloride to give 3-chlorobenzoylchloride, reaction of this acid chloride with 2-amino-2-methylpropanol to give the amide and cyclization of the amide with thionyl chloride followed by neutralization with dilute sodium hydroxide to give 2-(3-chlorophenyl)-4,4-dimethyl-2-oxazoline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04347176 |
| 출처 데이터셋 | uspto-grants-1982_08 |
| ORD ID | ord-dcb4f6e5fd2d4a0eadbac218c26a245b |
| 출처 메모 | uspto-grants-1982_08 |