Tetrahydrofuran → 5-(6-Amino-pyrimidin-4-yloxy)-2,3-dihydro-indole-1-carboxylic acid [4-(4-ethyl-piperazin-1-ylmethyl)-phenyl]-amide

반응식

[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][N:6]([CH2:9][c:10]2[cH:11][cH:12][c:13]([NH:16][C:17](=[O:18])[N:19]3[CH2:20][CH2:21][c:22]4[cH:23][c:24]([O:28][c:29]5[n:30][cH:31][n:32][c:33]([N:35]=[N+:36]=[N-:37])[cH:34]5)[cH:25][cH:26][c:27]43)[cH:14][cH:15]2)[CH2:7][CH2:8]1.[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1>>[CH2:1]([CH3:2])[N:3]1[CH2:4][CH2:5][N:6]([CH2:9][c:10]2[cH:11][cH:12][c:13]([NH:16][C:17](=[O:18])[N:19]3[CH2:20][CH2:21][c:22]4[cH:23][c:24]([O:28][c:29]5[n:30][cH:31][n:32][c:33]([NH2:35])[cH:34]5)[cH:25][cH:26][c:27]43)[cH:14][cH:15]2)[CH2:7][CH2:8]1

참가 물질

반응물 2

HCID 8028Tetrahydrofuran

HCID 595964065-(6-Azido-pyrimidin-4-yloxy)-2,3-dihydro-indole-1-carboxylic acid [4-(4-ethyl-piperazin-1-ylmethyl)-phenyl]-amide

생성물 1

HCID 595963875-(6-Amino-pyrimidin-4-yloxy)-2,3-dihydro-indole-1-carboxylic acid [4-(4-ethyl-piperazin-1-ylmethyl)-phenyl]-amide

출처 및 근거

ORD 기록: ord-8a7a4da36cf34d36807469ae2d51469c
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

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