5-Bromopyridine-2-carbonitrile → 5-(2-Fluoro-phenoxy)-2-pyrazin-2-yl-6-(6-cyano-pyridin-3-yloxy)-1H-benzimidazole

반응식

[Br:25][c:26]1[cH:27][cH:28][c:29]([C:32]#[N:33])[n:30][cH:31]1.[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][c:7]3[c:8]([nH:9][c:10](-[c:12]4[n:13][cH:14][cH:15][n:16][cH:17]4)[n:11]3)[cH:18][c:19]2[OH:20])[cH:21][cH:22][cH:23][cH:24]1>>[F:1][c:2]1[c:3]([O:4][c:5]2[cH:6][c:7]3[c:8]([nH:9][c:10](-[c:12]4[n:13][cH:14][cH:15][n:16][cH:17]4)[n:11]3)[cH:18][c:19]2[O:20][c:26]2[cH:27][cH:28][c:29]([C:32]#[N:33])[n:30][cH:31]2)[cH:21][cH:22][cH:23][cH:24]1

참가 물질

반응물 2

HCID 8171545-Bromopyridine-2-carbonitrile

HCID 1356979845-(2-fluorophenoxy)-6-hydroxy-2-pyrazin-2-yl-1H-benzimidazole

생성물 1

HCID 231451425-(2-Fluoro-phenoxy)-2-pyrazin-2-yl-6-(6-cyano-pyridin-3-yloxy)-1H-benzimidazole

출처 및 근거

ORD 기록: ord-7852b0e0d2214da297d85b10054dc0d7
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

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