Water → 2-Cyclopenten-1-one, 4-hydroxy-3-methyl-2-(2-propen-1-yl)-

HRID 68019

반응식

HRID 68019 반응식
O[C:2]1([CH3:11])[CH:6]([CH2:7][CH:8]=[CH2:9])[C:5](=[O:10])[CH:4]=[CH:3]1.[Cl-].[Na+].[OH2:14]>>[CH2:7]([C:6]1[C:5](=[O:10])[CH2:4][CH:3]([OH:14])[C:2]=1[CH3:11])[CH:8]=[CH2:9]

참가 물질

4

반응물 3

HCID 962WaterHCID 5234Sodium ChlorideHCID 128798724-Hydroxy-4-methyl-5-(prop-2-en-1-yl)cyclopent-2-en-1-one

생성물 1

HCID 110832-Cyclopenten-1-one, 4-hydroxy-3-methyl-2-(2-propen-1-yl)-

실험 절차

In an autoclave, 4-hydroxy-4-methyl-5-allyl-2-cyclopentenone (20 g) and water (400 ml) were charged, and the resultant mixture was stirred at 180° C. for 6 hours in a nitrogen atmosphere. After cooling, sodium chloride (50 g) was added to the reaction mixture, and the resulting mixture was extracted with methyl isobutyl ketone. The extract was concentrated under reduced pressure to give 2-allyl-3-methyl-4-hydroxy-2-cyclopentenone (19 g). Yield, 95%. M.P. 130°-132° C./1.2 mmHg.

후처리

  1. temperatureAfter cooling
  2. extractionthe resulting mixture was extracted with methyl isobutyl ketone
  3. concentrationThe extract was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-8371605ffe1349dc8bb6c0fe1adc2020
출처 데이터셋
uspto-grants-1982_08
특허 번호
US04347386

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