N-ethyl-3-methyl-6-nitroquinolin-2-amine → n2-Ethyl-3-methylquinoline-2.6-diamine

HRID 6806

반응식

HRID 6806 반응식
[CH2:1]([NH:3][C:4]1[C:13]([CH3:14])=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[C:9]([N+:15]([O-])=O)[CH:10]=2)[N:5]=1)[CH3:2]>CO.[Pt]=O>[CH2:1]([NH:3][C:4]1[C:13]([CH3:14])=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[C:9]([NH2:15])[CH:10]=2)[N:5]=1)[CH3:2]

참가 물질

4

반응물 1

HCID 22018880N-ethyl-3-methyl-6-nitroquinolin-2-amine

생성물 1

HCID 85837566n2-Ethyl-3-methylquinoline-2.6-diamine

시약·촉매·용매 2

HCID 82844Platinum oxide (PtO)촉매HCID 887Methanol용매

실험 절차

The product (0.8 g) of Step B and platinum oxide on carbon (˜80 mg) was suspended in methanol. The resulting mixture was hydrogenated at 50 PSI for 1 h. The reaction mixture was filtered through filter aid and the solvent removed under vacuum to afford the product, which was used without further purification.

후처리

  1. filtrationThe reaction mixture was filtered
  2. filtrationthrough filter aid
  3. customthe solvent removed under vacuum
  4. customto afford the product, which
  5. customwas used without further purification

출처 및 근거

ORD 기록
ord-bc1ae466ad6d421a8c6e6bc08d31abd8
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07084156B2

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